• Noninvasive cancer that originates in lobules or ducts.
  • Typically asymptomatic and diagnosed at screening.
  • Tamoxifen can be used to prevent ductal carcinoma in situ (DCIS) disease progression and lobular carcinoma in situ (LCIS) progression to invasive carcinoma.
  • Screening is recommended by most organizations issuing guidelines, in all women aged ≥40 years with annual bilateral mammography.
  • Diagnosis is with mammography, supplemented with other imaging, such as ultrasound or MRI, and biopsy.
  • Some patients may decide to have preventive bilateral mastectomy.
  • There are different approaches. Margin width remains something that is debated.

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